Tumor Necrosis Factor-α Promotes Malignant Pleural Effusion
نویسندگان
چکیده
منابع مشابه
Mutant KRAS promotes malignant pleural effusion formation
Malignant pleural effusion (MPE) is the lethal consequence of various human cancers metastatic to the pleural cavity. However, the mechanisms responsible for the development of MPE are still obscure. Here we show that mutant KRAS is important for MPE induction in mice. Pleural disseminated, mutant KRAS bearing tumour cells upregulate and systemically release chemokine ligand 2 (CCL2) into the b...
متن کاملTumor markers for diagnosing malignant pleural effusion?
1 Burgess DS. Pharmacodynamic principles of antimicrobial therapy in the prevention of resistance. Chest 1999; 115:19S– 23S 2 Craig WA. Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis 1998; 26:1–12 3 Poen AC, Felt-Bersma RJF, Van Dogen PAM, et al. Effect of prucalopride, a new enterokinetic agent, on gastrointestinal transit and an...
متن کاملMalignant pleural effusion.
Malignant pleural effusion (MPE) refers to the presence of neoplastic cells in the pleural fluid. Approximately 40 000 people per year in the UK are affected by MPE and it is associated with significant morbidity and an overall poor prognosis. Management should be prompt and care plans should be individualized and involve a multidisciplinary team of healthcare professionals. This article review...
متن کاملDiagnostic accuracy of tumor necrosis factor-alpha, interferon-gamma, interlukine-10 and adenosine deaminase 2 in differential diagnosis between tuberculous pleural effusion and malignant pleural effusion
BACKGROUND The current study was performed to investigate the potential biomarkers for the differential diagnosis of tuberculous pleural effusion (TPE) and malignant pleural effusions (MPE). METHODS Among ninety patients (n = 90) involved in the study, 47 with tuberculous pleural effusion aged from 18 to 70 and 43 with secondary malignant pleural effusion aged from 34 to 78. We tested the ple...
متن کاملMalignant pleural effusion.
Kathleen Shuey, MS, RN, AOCN®, APRN, BC, is an associate director at US Oncology in Houston, TX, and Yvette Payne, MSN, MBA, RN, APN, is an associate director of Clinical Affairs–Oncology at Ortho Biotech Clinical Affairs, LLC, in Tampa, FL. (Mention of specifi c products and opinions related to those products do not indicate or imply endorsement by the Clinical Journal of Oncology Nursing or t...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2007
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-07-1064